The library

tdmcp-pipeline · When you have an approved feature and want a coordinated team to ship it to production with quality gates.

art · When you need quick visual asset generation aligned to a design brief without manual design work.

autoresearch · When running overnight experiment loops with strict keep-or-discard decisions on single-variable changes.

awwwards-animations · When scroll-driven animations must hit 60fps on high-refresh displays with precise ScrollTrigger integration.

awwwards-ui-skills · When domain-specific guidance is required.

biopython · Computational biology tasks like sequence alignment, BLAST searches, structure parsing, or phylogenetic analysis.

frontend-engineer · Building production-quality web UIs when TypeScript strictness, accessibility, and responsive design are mandatory.

blockchain-web3-core · Loading plugins or optional modules at runtime when keeping main bundle size small is a priority.

blockchain-web3-orchestrator · Parallelizing research or batch enrichment when one supervising agent can fan out and aggregate work.

blueprint · Converting unstructured notes or reports into queryable structured data at scale with confidence tracking.

adaptyv · High-throughput binding screens when in-house lab unavailable

connectors-directory-spec · Local MCP discovery in Claude Desktop without hosting infrastructure

browser-automation-core · Deciding which browser/UI automation spoke to invoke

aeon · Temporal pattern detection faster/more accurate than standard ML

anndata · Single-cell genomics where scverse integration is mandatory

browser-extension-builder · Browser feature extensions that run user-side without server

arboreto · Fast GRN discovery when bulk sequencing data unavailable

browser-qa · Rapid QA coverage when manual testing is bottleneck

browser · One-shot diagnostics and deployment verification

bgpt-paper-search · Biotech literature review when Google Scholar insufficient

/telescope skill · When validating cross-level consistency in multi-layer analysis (micro/meso/macro) to catch real vertical analysis bugs.

cobrapy · Systems biology workflows requiring genome-scale metabolic model analysis.

tdmcp-submission · Preparing and re-preparing Anthropic Connectors Directory submissions.

b123d-drawing · Generating publication-quality 2D chemical structure images from SMILES.

flstudio-production · Music production workflows integrating algorithmic composition with DAW.

excalidraw-diagram-design · Creating hand-drawn style system diagrams when you want visual clarity without the stiffness of Visio or PlantUML.

flowzap-diagrams · Quickly iterating on process flowcharts and decision trees when you need automatic layout and export.

luxury-frontend-design · Client-facing high-end e-commerce, SaaS landing pages, or luxury event sites where visual polish directly impacts conversion and brand perception.

histolab · Cancer histopathology or tissue classification when patch-level features matter more than whole-slide; enables GPU-scale training on high-res scans.

ensembl-annotation · Genomics workflows where you need canonical gene structure, variant consequences, or cross-species orthologs; authoritative source (if on-date).

hugging-science · Rapid iteration on NLP/CV scientific tasks where pre-trained backbone beats training from scratch; HF Hub democratizes state-of-art.

epigenome-profiling · Cancer or developmental biology where multi-mark epigenome profiles reveal tumor states or differentiation trajectories better than single assay.

functional-screen-analysis · Functional genomics when you have CRISPR/RNAi data and need to rank candidates by statistical rigor; MAGeCK gold standard.

geo-connector · Finding complementary expression datasets in GEO that validate or extend ENCODE regulatory findings

imaging-data-commons · Accessing large-scale radiology and pathology datasets for AI training without authentication

gnomad-variants · Filtering ENCODE regulatory variants by population rarity and assessing gene constraint before functional validation

gtex-expression · Validating that genes near ENCODE regulatory elements are actually expressed in the matching tissue

gwas-catalog · Finding GWAS variants that overlap ENCODE regulatory elements to identify disease-associated regulatory effects

hic-aggregation · Comparing 3D genome structure across cell types by aggregating replicate Hi-C experiments

lamindb · Building a lineage-tracked, versioned registry of biological datasets for reproducible analysis

histone-aggregation · Creating robust consensus histone modification profiles by aggregating multiple ChIP-seq replicates

conducty-shape · Medium/high-complexity goals where requirements are unclear and scope needs bounding before implementation.

markdown-mermaid-writing · Technical narratives where inline diagrams clarify concepts without external tool switching.

market-research-reports · Go/no-go decisions where market sizing and competitive threat assessment are the binding constraints.

medchem · Designing drug molecules with integrated ADME and toxicity assessment.

flags · Quickly debugging why a feature behaves differently across canary/next/experimental channels.

publication-trust · Deciding whether to build downstream analysis on a paper's methods before wasting resources on unreliable findings.

quality-assessment · Quickly deciding if a sequencing sample meets publication standards without manual QC checklist.

scientific-writing · Rapidly drafting a paper outline before filling in analyses, rather than starting from a blank page.

speckit-tasks · Spec Kit workflow Phase 4 (tasks generation) when translating designs into implementation dependencies.