Analyze protein sequences and structure

full_protein_analysisskillsetup L3★147
InternScience/scp ↗
What it does

Analyze protein structures, interactions, and functional domains from sequences or PDB files

Best for

Rapidly characterizes unknown proteins by identifying homologs, domains, and predicted 3D structure.

Inputs
  • · [object Object]
  • · [object Object]
  • · [object Object]
Outputs
  • · [object Object]
  • · [object Object]
  • · [object Object]
Requires
  • · BLAST
  • · InterProScan
  • · Pymol
  • · DSSP
  • · FoldSeek
Preconditions

FASTA or PDB file, reference database access

Failure modes

Sequence too short for reliable homology; PDB missing cofactors affects structure interpretation

Trust signals
  • · BLAST E-value statistics
  • · Pfam domain confidence scores
  • · Structure validation (Ramachandran)